2. Signaling Pathways
  3. Epigenetics
  4. Histone Acetyltransferase
  5. Histone Acetyltransferase Modulator

Histone Acetyltransferase Modulator

Histone Acetyltransferase Isoform Comparison

Histone Acetyltransferase Modulators (4):

Cat. No. Product Name Effect Purity
  • HY-18935
    CBL0137
    		Modulator 99.68%
    CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-?B and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis.
  • HY-153768
    KAT modulator-1
    		Modulator ≥98.0%
    KAT modulator-1 (Compound 3) is a KAT modulator. KAT modulator-1 can interact with p300 full-length but not with the catalytic domain. KAT modulator-1 can be used for epigenetics research.
  • HY-152242
    YEATS4-IN-1
    		Modulator
    YEATS4-IN-1 (Compound 4d) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a Ki value of 33 nM.
  • HY-152243
    YEATS4 binder-1
    		Modulator
    YEATS4 binder-1(4e) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a Ki value of 37 nM.